Table 1 Minimum inhibitory concentrations (MICs) of ZF 52 crude and semi purified extracts and compound 1 (3a,10b-dimethyl-1,2,3,3a,5a,7,10b,10c-octahydro-5,8-dioxa-acephenanthrylene-4,9-dione) against P. aeruginosa.

From: Anti-Pseudomonas aeruginosa activity of a C16-terpene dilactone isolated from the endophytic fungus Neofusicoccum luteum of Kigelia africana (Lam.)

Extracts/compound

Fungal age

MIC (µg/mL)

ZF 52

T1

156.50

ZF 52

T2

39.06

ZF 52

T3

78.73

ZF 52

T4

19.53

Fraction C (partially purified ZF 52)

N/A

2.44

Compound 1

N/A

0.61

Gentamycin

N/A

4.00

  1. Gentamycin served as the positive control.
  2. T1, T2, T3, and T4 represent weeks 1, 2, 3 and 4, respectively in the fungal culture period. N/A = not applicable.