Table 3 Overview of the prospective cohort of cases with biopsy or surgical resection (n = 12).

From: Molecular analysis of cyst fluids improves the diagnostic accuracy of pre-operative assessment of pancreatic cystic lesions

Age/sex

Pathogenic variants

Cytologya

Histology

38 f

None

Negative

B: Autoimmune pancreatitis type 2

73 f

KRAS, TP53

Positive

B: Invasive adenocarcinoma

84 f

KRAS, TP53

Positive

B: Invasive adenocarcinoma

80 m

KRAS

Negative

B: Invasive adenocarcinoma

84 m

KRAS

Negative

B: Invasive adenocarcinoma

75 f

KRAS

Negative

S: IPMN gastric LG

58 f

None

Non-sufficient

S: SCN

81 m

SMAD4

Negative

S: Invasive adenocarcinoma and IPMN intestinal LG

37 f

KRAS, TP53

Suspicious

S: Invasive adenocarcinoma arisen from MCN HG

56 m

KRAS, TP53, SMAD4

Negative

S: Invasive adenocarcinoma arisen from IPMN gastric HG

74 f

KRAS

Negative

S: Invasive adenocarcinoma

71 m

KRAS

Equivocal

S: MCN LG

  1. B biopsy, S surgical resection, f female, m male, HG high grade, IPMN intraductal papillary mucinous neoplasm, LG low grade, MCN mucinous cystic neoplasm, SCN serous cystic neoplasm.
  2. aNon-sufficient/negative/equivocal/suspicious/positive: interpretation according to German classification48.
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