Table 1 Clinical characteristics, thrombotic events and outcomes of patients with SARS-CoV-2 and non-CoV-2 respiratory viruses.

From: Clinical and laboratory features of hypercoagulability in COVID-19 and other respiratory viral infections amongst predominantly younger adults with few comorbidities

 

SARS-CoV-2 (n = 182)

Non-CoV-2 respiratory viruses (n = 165)

P values

Demographics

Age, Median (IQR)

37 (30.51)

35 (29.51)

0.122

Gender—no.(%)

  

 < 0.001

 Male

133 (73.1)

87 (52.7)

 

 Female

49 (26.9)

78 (47.3)

 

Race—no.(%)

  

 < 0.001

 Chinese

63 (34.6)

74 (44.8)

 

 Malay

6 (3.3)

31 (18.8)

 

 Indian

81 (44.5)

35 (21.2)

 

 Others

32 (17.6)

25 (15.2)

 

Comorbidities—no.(%)

Hypertension

44 (24.2)

28 (17.0)

0.098

Hyperlipidemia

15 (8.20)

24 (18.50)

0.063

Diabetes Mellitus

10 (5.5)

22 (13.3)

0.012

Ischemic Heart Disease

6 (3.30)

13 (7.90)

0.061

Prior stroke

4 (2.20)

5 (3.0)

0.626

Renal disease

1 (0.50)

10 (6.10)

0.003

Chronic lung disease

18 (9.90)

15 (9.10)

0.800

Liver disease

0 (0.00)

3 (1.80)

0.106

Active malignancy

0 (0.00)

3 (1.80)

0.106

Charlson Comorbidity index

 Median (IQR)

0 (0.1)

0 (0.1)

0.39

 0–2 points

167 (91.8)

145 (87.9)

0.231

 ≥ 3 points

15 (8.2)

20 (12.1)

 

Existing antithrombotic agentsno.(%)

Antiplatelet

8 (4.4)

7 (4.2)

1.0

Anticoagulation

1 (0.5)

1 (0.6)

1.0

Thrombotic outcomes

Arterial thrombosis—no.(%)

2 (1.1)

1 (0.6)

1.0

Venous thrombosis—no.(%)

0

0

Event/1000 patient days

1.0

1.8

0.6308

Outcomes

Required O2 supplementation—no.(%)

20 (11.0)

8 (4.8)

0.035

HD—no.(%)

2 (1.1)

0 (0)

0.500

ICU—no.(%)

9 (4.9)

2 (1.2)

0.047

LOS in ICU, median (IQR)

20 (9.27)

5 (3.7)

0.073

Total patient days in ICU

160

10

LOS, Median (IQR)

7.5 (6.13)

3 (2.3)

 < 0.001

Total patient days in hospital

1979

554

Death—no.(%)

2 (1.1)

1 (0.6)

1.0