Table 5 Gastric AA evaluation parameters against ethanol-induced gastric injury in rats.

From: Formulation, optimization and characterization of allantoin-loaded chitosan nanoparticles to alleviate ethanol-induced gastric ulcer: in-vitro and in-vivo studies

Group

UA (mm2)

UI

PI

pH

N

–

–

–

4.8 ± 0.05

Ulcer

165.2 ± 45.96

7.79 ± 2.71

–

3.4 ± 0.06#

Ome

27.33 ± 12.17***

1.59 ± 0.64

79.62

4.52 ± 0.07***

Plain

22.74 ± 14.45***

1.54 ± 0.79

80.18

3.8 ± 0.14*,@

ALL

23.16 ± 16.8***

1.45 ± 0.94

81.33

3.9 ± 0.02**,@

NanoAL

4.725 ± 3.55***

0.23 ± 0.13*

97.07

4.45 ± 0.11***,^,%

NanoAH

2.99 ± 1.32***

0.211 ± 0.11*

97.29

4.34 ± 0.07***,^,%

  1. Data are expressed as mean ± SEM, #p < 0.001 compared to N group, *p < 0.05 compared to ulcer group; **p < 0.01 compared to ulcer group; ***p < 0.001 compared to ulcer group; @p < 0.001 compared to ulcer group; ^p < 0.01 compared to plain group; %p < 0.05 compared to ALL group.
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