Figure 7 | Scientific Reports

Figure 7

From: Influence of energy deficiency on the subcellular processes of Substantia Nigra Pars Compacta cell for understanding Parkinsonian neurodegeneration

Figure 7

Responses of whole (A–D) and reduced (E–H) models to hypoglycemia and hypoxia conditions. Average normal alpha-synuclein (asyn) concentration (A,E), average misfolded alpha-synuclein (asynmis) concentration (B,F), average aggregated alpha-synuclein (asynagg) concentration (C,G), and average reactive oxygen species (ROS) concentration (D,H) of the fast and slow dynamic models for varying glucose and oxygen concentrations. conc concentration, mM millimolar.

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