Table 3 Hazard ratios and 95% confidence intervals for the incidence of composite of end-stage renal disease and all-cause mortality according to the categories of diastolic blood pressure among the individuals with chronic kidney disease.

From: Optimal blood pressure for patients with chronic kidney disease: a nationwide population-based cohort study

Categories of DBP (mmHg)

Composite of end-stage renal disease and all-cause death

Events (n)

Follow-up duration (person-years)

Incidence rate (per 1000 person-years)

Adjusted HR (95% CI)*

Total

 < 60 (n = 358)

26

2081

12.49 (8.51–18.35)

1.401 (0.940–2.088)

60–69 (n = 2964)

141

17,632

8.00 (6.78–9.43)

1.022 (0.840–1.243)

70–79 (n = 7373)

346

44,082

7.85 (7.06–8.72)

1 (Ref.)

80–89 (n = 8567)

452

51,341

8.80 (8.03–9.65)

1.150 (0.999–1.322)

90–99 (n = 2230)

184

13,040

14.11 (12.21–16.30)

1.458 (1.218–1.746)

 ≥ 100 (n = 786)

76

4619

16.45 (13.14–20.60)

1.733 (1.350–2.224)

P for trend

   

 < 0.0001

Non-users of antihypertensive agent

 < 60 (n = 214)

6

1274

4.71 (2.12–10.48)

1.087 (0.478–2.471)

60–69 (n = 1863)

35

11,306

3.10 (2.22–4.31)

0.762 (0.522–1.113)

70–79 (n = 4306)

115

26,129

4.40 (3.67–5.28)

1 (Ref.)

80–89 (n = 4503)

122

27,468

4.44 (3.72–5.30)

1.008 (0.781–1.301)

90–99 (n = 927)

50

5536

9.03 (6.85–11.92)

1.631 (1.169–2.275)

 ≥ 100 (n = 361)

17

2190

7.76 (4.83–12.49)

1.451 (0.870–2.417)

P for trend

   

0.0145

Users of antihypertensive agent

 < 60 (n = 144)

20

807

24.79 (15.99–38.43)

1.477 (0.935–2.333)

60–69 (n = 1101)

106

6326

16.76 (13.85–20.27)

1.141 (0.906–1.437)

70–79 (n = 3067)

231

17,953

12.87 (11.31–14.64)

1 (Ref.)

80–89 (n = 4064)

330

23,873

13.82 (12.41–15.40)

1.192 (1.007–1.410)

90–99 (n = 1303)

134

7504

17.86 (15.08–21.15)

1.345 (1.087–1.665)

 ≥ 100 (n = 425)

59

2429

24.29 (18.82–31.35)

1.825 (1.370–2.431)

P for trend

   

0.0042

  1. DBP diastolic blood pressure, HR hazard ratio, CI confidence interval.
  2. *Adjusted for age, sex, current smoking, alcohol consumption, regular exercise, household income level, body mass index, presence of dyslipidaemia, diabetes mellitus, and urine dipstick positivity for protein. Adjusted HRs (95% CIs) and P-values, considered to be statistically significant in bold font.