Figure 1
From: Homologous laminar organization of the mouse and human subiculum
Structural comparison of the mouse and human hippocampus. (a) Three-dimensional representations of the mouse and human hippocampus showing the relative locations of the DG/CA3 (yellow), CA1 (red), and SUB (green); see also Supplementary Movie 1 or use Schol-AR app). The longitudinal hippocampal axis (red in axes chart) in mouse is oriented dorsoventrally, whereas the human longitudinal axis is rotated into the anterior–posterior axis. In addition the anterior/posterior (septo-temporal; blue color) axis in mice is oriented in the superior-inferior direction in humans. (b) Sagittal view of human brain volume representing the spatial location of all in situ hybridization datasets from the Allen Human Brian Atlas (top). Two tissue blocks containing posterior (middle) and anterior (bottom) parts of the hippocampus (white arrows) are shown overlaid on sagittal 3 T structural MRI images. All images in (b) are from www.brain-map.org. Data viewable with Schol-AR augmented reality app, for details visit https://www.ini.usc.edu/scholar/download.html.
