Table 1 Serum/blood parameters at the end of the study.

From: Caloric restriction reduces sympathetic activity similar to beta-blockers but conveys additional mitochondrio-protective effects in aged myocardium

 

Co

CR

BB

DF

Glucose (mmol/l)

6.41 ± 0.08

5.79 ± 0.21*

6.45 ± 0.13#

6.54 ± 0.17#

Insulin (ng/ml)

1.20 ± 0.09

0.81 ± 0.13*

1.13 ± 0.24

0.98 ± 0.19

Leptin (pg/ml)

364 ± 21

160 ± 18**

220 ± 19*,#

396 ± 26##

Adiponectin (µg/ml)

5.49 ± 0.27

13.48 ± 1.01***

5.26 ± 0.53###

6.07 ± 0.33##

BNP (pg/ml)

66.51 ± 8.36

42.19 ± 9.14*

35.84 ± 8.39*

71.07 ± 9.61#

TBARS (µM)

34.65 ± 6.96

36.37 ± 5.52

30.62 ± 2.86

35.16 ± 3.39

Carbonyl (nmol/mg)

1.78 ± 0.23

1.54 ± 0.39

1.73 ± 0.32

1.82 ± 0.41

Adrenaline (pg/ml)

180 ± 15

171 ± 23

123 ± 29*

194 ± 34

Noradrenaline (pg/ml)

402 ± 37

326 ± 26*

286 ± 15**

496 ± 31*,#

  1. Co control diet, CR caloric restriction, BB beta-blocker, DF furosemide.
  2. *p < 0.05, **p < 0.01, ***p < 0.001 vs. respective control; #p < 0.05, ##p < 0.01, ###p < 0.001 vs. CR. All data are mean ± SEM (n = 10 per group).
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