Figure 5
From: Acetyl-CoA flux from the cytosol to the ER regulates engagement and quality of the secretory pathway
AT-1 sTg and AT-1S113R/+ display a highly heterogeneous cortical secretome. (a–d) Network of significant glycan types plotted to glycoprotein for cortical (a) AT-1 sTg female, (b) AT-1 sTg male, (c) AT-1S113R/+ female, and (d) AT-1S113R/+ male. Circle represents glycan type, with each node representing a specific glycan tree. Glycans intersect with their protein, organized by the number of glycosites identified on that glycoprotein. (e–h) Glycosylation distribution according to subcellular localizations as defined by GO cellular component terms in cortical (e) AT-1 sTg female, (f) AT-1 sTg male, (g) AT-1S113R/+ female, and (h) AT-1S113R/+ male.
