Figure 3 | Scientific Reports

Figure 3

From: Network analysis of Down syndrome and SARS-CoV-2 identifies risk and protective factors for COVID-19

Figure 3

Volcano plot of the TMPRSS2 and ACE2 genes. (A) Volcano plot showing on the x-axis the log2 fold change and the y-axis the significance (− log10 of the Benjamini-corrected p-value) across different DS transcriptomic studies detecting TMPRSS2. Red dots indicate contrasts with deregulation > 1.5 of absolute fold change (dashed blue lines) and < 0.05 adjusted p-value (dashed red line). (B) Same as in (A) but for ACE2.

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