Figure 2

Kidney morphologies in wild-type and miR29a transgenic mice with the control and DM animals. Coronal T2-weighted imaging of renal architecture in (a) WT NC and WT DM; (b) Tg NC and Tg DM. (c) Ratio of renal structures in control and STZ induced DM with time variation. Data are analyzed and expressed as the mean ± SEM calculated from six mice at each time point. ** < 0.01 and *** < 0.001 with one-way ANOVA analysis, significant difference between each group. WT, wild-type; Tg, miR29a transgenic mice; NC, normal control; DM, diabetic mice. ROIs of Renal architecture with renal cortex (CO), outer stripe of the outer medulla (OSOM), inner stripe of the outer medulla (ISOM), and inner medulla (IM).