Figure 3

Comparison of DCE-MRI for wild-type and miR29a transgenic mice as the control and DM animals. (a) DCE-MR imaging with Ktrans mapping of kidneys in each experimental group from vascular-phase images, and the unit of the color bar is mL/min/1000 mL; (b) value of Ktrans in renal cortex structures with control and STZ induced DM groups; (c) value of Ktrans in renal medulla structures with control and STZ induced DM groups. (* < 0.05 with one-way ANOVA analysis, significant difference between each group; WT, wild-type; Tg, miR29a transgenic mice; NC, normal control; DM, diabetic mice; n = 5).