Figure 4

Apparent diffusion coefficient (ADC) mapping of kidneys in control and DM groups. (a) WT control and DM; (b) miR29a Tg control and DM. ADC mapping was decreased during STZ-induced DM model. ROIs were copied from b0 images to ADC mapping, and ADC values were calculated separately for all anatomic layers at different times (c). (* < 0.05, ** < 0.01, and *** < 0.001 with one-way ANOVA analysis, significant difference between groups).