Table 1 Distribution of molecular subtypes, menopausal status, tumor size, malignancy grade, and sentinel node (SN) status for 1556 patients.
From: Clinical implications of intrinsic molecular subtypes of breast cancer for sentinel node status
Molecular subtype | NormL | LumA | LumB | LumC | mApo | BasL | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
No. of patients (%)* | 339 (22) | 597 (38) | 230 (15) | 149 (10) | 71 (5) | 170 (11) | ||||||
Menopause | ||||||||||||
Premenopause | 87 (26) | 117 (20) | 69 (30) | 42 (28) | 12 (17) | 68 (40) | ||||||
Postmenopause | 252 (74) | 480 (80) | 161 (70) | 107 (72) | 59 (83) | 102 (60) | ||||||
Tumor size | ||||||||||||
11–20 mm | 232 (68) | 381 (64) | 120 (52) | 94 (63) | 39 (55) | 94 (55) | ||||||
> 20 mm | 107 (32) | 216 (36) | 110 (48) | 55 (37) | 32 (45) | 76 (45) | ||||||
Grade | ||||||||||||
1 | 159 (47) | 210 (35) | 15 (7) | 20 (13) | 2 (3) | 0 (0) | ||||||
2 | 168 (50) | 323 (54) | 113 (49) | 71 (48) | 16 (23) | 14 (8) | ||||||
3 | 6 (2) | 38 (6) | 99 (43) | 54 (36) | 46 (65) | 144 (85) | ||||||
N/A | 6 (2) | 26 (4) | 3 (1) | 4 (3) | 7 (10) | 12 (7) | ||||||
SN status | ||||||||||||
SN-negative | 232 (68) | 370 (62) | 143 (62) | 92 (62) | 49 (69) | 134 (79) | ||||||
SN-positive | 107 (32) | 227 (38) | 87 (38) | 57 (38) | 22 (31) | 36 (21) |
SN- | SN + | SN- | SN + | SN- | SN + | SN- | SN + | SN- | SN + | SN- | SN + | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
No systemic treatment | 13 (6) | 4 (4) | 21 (6) | 5 (2) | 6 (4) | 1 (1) | 2 (2) | 4 (7) | 6 (12) | 1 (5) | 15 (11) | 2 (6) |
ET only | 167 (72) | 52 (49) | 258 (70) | 134 (59) | 59 (41) | 21 (24) | 37 (40) | 20 (35) | 4 (8) | 4 (18) | 4 (3) | 0 (0) |
ET + CT | 43 (19) | 44 (41) | 65 (18) | 74 (33) | 69 (48) | 60 (69) | 44 (48) | 27 (47) | 6 (12) | 9 (41) | 23 (17) | 12 (33) |
CT only | 2 (1) | 3 (3) | 4 (1) | 3 (1) | 3 (2) | 2 (2) | 3 (3) | 4 (7) | 25 (51) | 7 (32) | 79 (59) | 20 (56) |
No registration (N/A) | 7 (3) | 4 (4) | 22 (6) | 11 (5) | 6 (4) | 3 (3) | 6 (7) | 2 (4) | 8 (16) | 1 (5) | 13 (10) | 2 (6) |
(%) col |
