Figure 4

Identification of dysregulated genes by intestine-specific RNAi knockdown of linc-50 in simulated microgravity treated nematodes. (a) Heatmap showing expression of dysregulated genes in simulated microgravity treated nematodes with intestine-specific RNAi knockdown of linc-50. The heatmap was drawn using Omicshare (www.omicshare.com/tools/), a free access online analysis tool of bioinformatics. (b) Upregulated genes induced by intestine-specific RNAi knockdown of linc-50 in simulated microgravity treated nematodes. N = 3. (c) Downregulated genes induced by intestine-specific RNAi knockdown of linc-50 in simulated microgravity treated nematodes. N = 3. Simulated microgravity treatment was performed in RCCS system at 30 rpm for 24 h.