Table 3 Important signaling pathways and major DEGs involved in these pathways.

From: Transcriptome profiling of cells exposed to particular and intense electromagnetic radiation emitted by the "SG-III" prototype laser facility

Signaling pathway

Up-regulated degs

Down-regulated degs

TNF signaling pathway

Map3k14

Fos, Ccl2, Junb, Cxcl1, Birc3, Lif, Atf4

PI3K-Akt signaling pathway

Thbs1, Ngfr, Ngf, Col6a3

Col2a1, Col9a2, Itga2, Vegfa, Ntrk2, Ddit4, Nr4a1, Irs1, Atf4

MAPK signaling pathway

Ngfr, Ngf, Flnc

Fos, Dusp6, Mef2c, Vegfa, Ntrk2, Gadd45b, Nr4a1, Dusp4, Atf4

Transcriptional misregulation in cancer

Ngfr

Nfkbiz, Nr4a3, Dusp6, Mef2c, Gadd45b, Mitf, Birc3

cGMP-PKG signaling pathway

Nppb

Mef2c, Prkg1, Irs1, Plcb1, Atf4, Cngb1

Viral protein interaction with cytokine and cytokine receptor

Ackr3

Ccl2, Ccl7, Cxcl1, Cxcl11

Micrornas in cancer

Thbs1

Vegfa, Mir27b, Ddit4, Spry2, Mir7a-1, Irs1, Socs1

Focal adhesion

Thbs1, Flnc, Col6a3

Col2a1, Col9a2, Itga2, Vegfa, Birc3, Pip5k1b

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