Table 5 Cox proportional hazard regression model describing long-term risk of ESRD of ANCA-related renal vasculitis patients.
Parameter | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
HR (95%CI) | P value | HR (95%CI) | P value | |
Systolic BP (mmHg) | 1.010 (0.994–1.027) | 0.214 | ||
Diastolic BP (mmHg) | 1.014 (0.967–1.063) | 0.563 | ||
Serum creatinine(µmol/L) | 1.004 (1.002–1.006) | < 0.001 | 1.000 (0.995–1.005) | 0.987 |
eGFR (ml/min/1.73 m2) | 0.927 (0.879–0.978) | 0.005 | 0.951 (0.879–1.029) | 0.212 |
Uric acid (µmol/L) | 1.009 (1.004–1.013) | 0.001 | 1.007 (1.001–1.013) | 0.016 |
Total cholesterol (mmol/L) | 0.933 (0.624–1.397) | 0.737 | ||
Triglycerides (mmol/L) | 1.280 (0.648–2.526) | 0.477 | ||
CRP (mg/L) | 0.992 (0.980–1.004) | 0.169 | ||
Normal glomeruli (%) | 0.959 (0.931–0.988) | 0.006 | 0.944 (0.896–0.996) | 0.034 |
Crescent (%) | 1.021 (1.000–1.042) | 0.052 | 0.977 (0.939–1.016) | 0.242 |
Fibrous crescent (%) | 1.029 (1.012–1.045) | 0.001 | 1.015 (0.983–1.048) | 0.350 |
Tubular atrophy integral | 2.524 (1.507–4.228) | < 0.001 | 1.267 (0.595–2.697) | 0.540 |
Interstitial fibrosis integral | 1.537 (0.991–2.384) | 0.055 | 1.037 (0.630–1.707) | 0.888 |
