Table 5 Results of microarray analysis of the 12 genes that were selected for further investigation by real-time PCR.

From: Molecular characterisation of osteoblasts from bone obtained from people of Polynesian and European ancestry undergoing joint replacement surgery

 

Gene symbol

 

Fold change

P value

1

COL1A1

Collagen type I alpha 1 chain

1.51

0.00007

2

ALPL

Alkaline phosphatase

1.5

0.01

3

BGLAP

Bone gamma-carboxyglutamate protein (osteocalcin)

1.08

0.57

4

IBSP

Integrin binding sialoprotein

 − 1.79

0.27

5

KRT34

Keratin 34

2.61

0.0002

6

CCND1

Cyclin D1

2.12

0.0017

7

EFNB2

Ephrin B2

 − 1.66

0.0147

8

CDH13

Cadherin 13

 − 1.69

0.0203

9

WISP2

Wnt1-inducible signaling pathway protein-2

 − 1.89

0.0006

10

NOV

Nephroblastoma overexpressed

 − 2.12

0.0012

11

DKK1

Dickkopf 1

 − 2.16

0.0078

12

EFHD1

EF-hand domain family member D1

 − 2.59

0.00004

  1. Data expressed as Log2 mean fold change, Polynesian/European.
  2. Rows 1–4, osteoblast marker genes; rows 5–12, other genes.
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