Table 9 Antigenicity, allergenicity and solubility Evaluation Results. NA: non-allergen. Higher Vaxijen and Antigen Pro scores suggest higher antigenicity. Higher SolPro and Protein-sol scores suggest higher solubility.
From: An in silico deep learning approach to multi-epitope vaccine design: a SARS-CoV-2 case study
Vaccine subunits | Vaxijen score | Antigen pro score | AllerTOP result | Allergen FP result | Solubility by SolPro | Solubility by protein-sol |
|---|---|---|---|---|---|---|
Adjuvant | 0.7447 | 0.8205 | NA | NA | 0.7568 | 0.716 |
Subunit 1 | 0.2486 | 0.4137 | NA | NA | 0.5890 | 0.684 |
Subunit 3 | 0.4791 | 0.5923 | NA | NA | 0.8113 | 0.660 |
Subunit 4 | 0.3891 | 0.7364 | NA | NA | 0.6242 | 0.608 |
Subunit 5 | 0.4757 | 0.4768 | NA | NA | 0.7819 | 0.686 |
Subunit 10 | 0.3615 | 0.6256 | NA | NA | 0.6023 | 0.652 |
Subunit 13 | 0.8318 | 0.4032 | NA | NA | 0.9114 | 0.730 |
Subunit 18 | 0.2449 | 0.3076 | NA | NA | 0.9928 | 0.742 |
Subunit 19 | 0.3605 | 0.4991 | NA | NA | 0.7831 | 0.636 |
Subunit 23 | 0.6713 | 0.7355 | NA | NA | 0.6891 | 0.640 |
Subunit 24 | 0.4012 | 0.5211 | NA | NA | 0.9747 | 0.545 |
Subunit 25 | 0.6035 | 0.7433 | NA | NA | 0.6425 | 0.947 |
Final Vaccine | 0.5705 | 0.8814 | NA | NA | 0.7555 | 0.723 |
