Figure 7
From: Protective effects of growth hormone-releasing hormone analogs in DSS-induced colitis in mice

Effect of MIA-690 (5 µg) and MR-409 (5 µg) (n = 6 for each group of treatment) s.c. administration on macroscopic and histopathological changes of colon in a model of DSS-induced colitis. A (a1 and a2): normal colon segment; B (b1 and b2), C (c1 and c2) and D (d1 and d2): inflammation of colon segment in DSS-induced colitis; necrosis of epithelium, distortion of crypts, inflammation, infiltrates in lamina propria and submucosa as well as submucosal edema. Hematoxilyn and eosin stain: the inserted bars indicate magnification. [H&E staining, × 10 (a1, b1, c1, d1); × 20 (a2, b2, c2, d2) original magnification].