Figure 5
From: Glucose confers protection to Escherichia coli against contact killing by Vibrio cholerae
Model depicting the proposed E. coli glucose-mediated protection mechanism against the V. cholerae C6706* T6SS. (a) When E. coli cells are grown on rich media in the absence of glucose, CRP is bound by cAMP and represses (directly or indirectly) an unknown gene (or genes). Repression of those genes results in higher susceptibility to T6SS attacks. (b) When E. coli cells are grown on rich media in the presence of glucose, CRP is not bound by cAMP and cannot repress the genes it controls under low glucose conditions. As a result, E. coli cells have increased protection against T6SS attack.
