Figure 4
The anti-AMH antibody B10 reduces COV434-MISRII tumor growth in vivo. Nude mice bearing COV434-MISRII cell tumors were treated with B10 (anti-AMH antibody), 12G4 (anti-AMHRII antibody) (10 mg/kg/injection for both), or vehicle (NaCl; control) twice a week for 4 weeks. (a) Tumor growth curves (mean + 95% confidence intervals), and (b) Kaplan–Meier survival curves (percentage of mice with a tumor volume < 1500 mm3 as a function of time after graft).
