Figure 1

Patient Characteristics and summary of clinically relevant gene mutations from the patient non-small cell lung cancer (NSCLC) brain metastasis samples in which patient-derived xenografts (PDXs) were established. Age at diagnosis, gender, smoking pack-years, synchronous brain metastasis, yes or no, prior radiotherapy yes or no, programmed death-ligand 1 (PD-L1) immunohistochemistry (IHC) percent positive.