Table 2 Temporal features (laboratory tests and vital signs). The table presents information on the full cohort (admitted and non-admitted SARS-CoV-2 positive patients) as well as subgroups admitted to a hospital and Intensive Care Unit (ICU) respectively.
Unit | All SARS-CoV-2 patients (n = 3944) | Non-hospitalized (n = 2585) | Hospitalized patients (n = 1359) | Hospitalized patients without ICU admission (n = 1178) | Hospitalized patients with ICU admission (n = 181) | Survivors (n = 3620) | Non-survivors (n = 324) | |
|---|---|---|---|---|---|---|---|---|
CRP | mg/l | 65.0 (29.0–122.0) | 21.0 (8.7–46.5) | 66.0 (30.0–124.0)** | 58.0 (26.0–110.0) | 142.0 (86.8–231.0)** | 59.5 (24.3–119.0) | 79.5 (42.0–160.0)** |
Lymphocyte count | 109/l | 0.9 (0.6–1.4) | 1.2 (0.8–1.7) | 0.9 (0.6–1.3)** | 10.0 (0.7–1.4) | 0.8 (0.5–1.1) | 1.0 (0.7–1.4) | 0.8 (0.6–1.1)** |
Lactic dehydrogenase | U/l | 274.5 (210.0–376.8) | 215.5 (176.5–234.3) | 277.5 (214.0–381.5)** | 263.0 (206.0–342.5) | 430.0 (323.0–579.0)** | 272.0 (207.0–366.5) | 292.0 (226.0–411.5)** |
Alanine aminotransferase | U/l | 27.0 (18.0–45.0) | 26.0 (17.5–35.0) | 27.5 (18.0–46.0)** | 26.0 (18.0–43.0) | 36.0 (23.3–62.0)** | 28.0 (19.0–46.3) | 25.0 (17.0–41.0)** |
Hemoglobin | mmol/l | 8.0 (7.1–8.7) | 8.3 (7.6–8.9) | 8.0 (7.1–8.7)** | 8.0 (7.1–8.8) | 7.6 (6.9–8.4) | 8.1 (7.2–8.8) | 7.7 (6.7–8.4)** |
White blood cells | 109/l | 6.8 (5.1–9.4) | 6.3 (4.7–7.3) | 6.8 (5.1–9.5)** | 6.8 (5.1–9.3) | 7.9 (5.3–10.6) | 6.7 (5.0–9.0) | 7.4 (5.6–10.7)** |
Neutrophil count | 109/l | 5.0 (3.5–7.4) | 4.15 (3.3–5.2) | 5.0 (3.5–7.5)** | 4.9 (3.5–7.1) | 6.1 (4.2–8.8) | 4.8 (3.4–6.9) | 5.7 (4.1–8.7)** |
D dimer | mg/l | 1.0 (0.6–2.4) | 0.7 (0.7–1.9) | 1.0 (0.6–2.4)** | 0.9 (0.5–2.1) | 1.4 (0.8–4.3)** | 0.9 (0.5–2.1) | 1.8 (0.8–4.4)** |
Blood urea nitrogen | mmol/l | 6.3 (4.3–9.9) | 4.3 (3.8–6.7) | 6.4 (4.4–10.0)** | 6.3 (4.4–9.9) | 6.8 (5.1–10.8) | 5.7 (4.1–8.4) | 9.8 (6.8–14.8)** |
Creatinine | umol/l | 81.5 (65.6–108.0) | 67.0 (58.0–85.0) | 83.0 (65.0–109.0)** | 82.0 (65.0–107.0) | 85.5 (67.0–111.3) | 79.0 (63.0–100.0) | 99.0 (75.6–149.0)** |
Ferritin | ug/l | 557.0 (203.0–1125.0) | 167.0 (99.0–613.0) | 570.0 (219.5–1145.0)** | 399.0 (176.3–913.3) | 1100.0 (741.0–1910.0)** | 516.0 (204.0–1140.0) | 649.0 (201.0–1110.0)** |
Base excess | mmol/l | 0.8 (− 1.4–3.0) | 0.3 (− 0.9–2.7) | 0.8 (− 1.4–3.1)** | 0.7 (− 1.4–3.0) | 1.0 (− 1.7–3.6) | 0.8 (− 1.1–3.1) | 0.6 (− 2.8–3.0) |
HCO3 | mEQ/l | 25.2 (23.6–27.0) | 25.0 (24.3–26.8) | 25.2 (23.6–27.0)** | 25.2 (23.6–26.9) | 25.4 (23.6–27.4)** | 25.3 (24.0–27.0) | 24.9 (22.2–27.0)** |
Lactate | mmol/l | 1.1 (0.8–1.5) | 1.2 (0.8–1.8) | 1.1 (0.8–1.5)** | 1.0 (0.8–1.5) | 1.3 (1.0–1.7)** | 1.0 (0.8–1.4) | 1.3 (0.9–1.7)** |
Arterial O2 saturation | % | 0.94 (0.92–0.99) | 0.95 (0.92–0.97) | 0.94 (0.92–0.97)** | 0.95 (0.92–0.97) | 0.92 (0.91–0.94)** | 0.95 (0.92–0.97) | 0.93 (0.92–0.96)** |
pCO2 | mmHg | 4.6 (4.1–5.1) | 4.7 (4.4–5.0) | 4.6 (4.1–5.1)** | 4.6 (4.1–5.1) | 4.7 (4.1–5.2)** | 4.6 (4.1–5.1) | 4.7 (4.0–5.2)** |
pH | – | 7.46 (7.43–7.49) | 7.47 (7.43–7.49) | 7.46 (7.43–7.49)** | 7.46 (7.43–7.49) | 7.47 (7.42–7.49)** | 7.47 (7.43–7.49) | 7.45 (7.41–7.49)** |
pO2 | mmHg | 9.1 (8.0–10.9) | 10.0 (7.9–10.7) | 9.1 (8.0–10.9)** | 9.4 (8.2–11.1) | 8.3 (7.5–9.6)** | 9.3 (8.2–11.1) | 8.8 (7.8–10.2)** |
Pulse | /min | 83.0 (72.0–94.0) | 86.0 (74.0–102.25) | 83.0 (72.0–93.0)** | 82.0 (71.0–92.0) | 86.0 (76.0–97.0) | 82.0 (72.0–93.0) | 85.0 (72.8–98.3)** |
Temperature | C | 37.4 (36.8–38.1) | 37.3 (36.6–38.0) | 37.4 (36.8–38.1)** | 37.3 (36.8–38.0) | 37.6 (37.1–38.3) | 37.4 (36.8–38.1) | 37.3 (36.7–38.0)** |
Early warning score | – | 3.0 (2.0–6.0) | 2.0 (1.0–4.0) | 4.0 (2.0–6.0)** | 3.0 (2.0–5.0) | 6.0 (5.0–8.0)** | 3.0 (2.0–5.0) | 5.0 (3.0–6.0)** |
Respiratory rate | /min | 20.0 (17.0–22.0) | 18.0 (16.0–20.0) | 20.0 (18.0–22.0)** | 20.0 (17.0–21.0) | 24.0 (20.0–30.0)** | 20.0 (17.0–22.0) | 20.0 (18.0–24.0)** |
Saturation | % | 96.0 (94.0–98.0) | 98.0 (96.5–99.0) | 96.0 (94.0–97.0)** | 96.0 (95.0–98.0) | 94.0 (92.0–95.0) | 96.0 (95.0–98.0) | 95.0 (93.0–97.0)** |
Is smoking | % | 4.8 | 0.5 | 13.1** | 12.1 | 19.3 | 3.4 | 21.3** |