Table 2 Temporal features (laboratory tests and vital signs). The table presents information on the full cohort (admitted and non-admitted SARS-CoV-2 positive patients) as well as subgroups admitted to a hospital and Intensive Care Unit (ICU) respectively.

From: Developing and validating COVID-19 adverse outcome risk prediction models from a bi-national European cohort of 5594 patients

 

Unit

All SARS-CoV-2 patients (n = 3944)

Non-hospitalized (n = 2585)

Hospitalized patients (n = 1359)

Hospitalized patients without ICU admission (n = 1178)

Hospitalized patients with ICU admission (n = 181)

Survivors (n = 3620)

Non-survivors (n = 324)

CRP

mg/l

65.0 (29.0–122.0)

21.0 (8.7–46.5)

66.0 (30.0–124.0)**

58.0 (26.0–110.0)

142.0 (86.8–231.0)**

59.5 (24.3–119.0)

79.5 (42.0–160.0)**

Lymphocyte count

109/l

0.9 (0.6–1.4)

1.2 (0.8–1.7)

0.9 (0.6–1.3)**

10.0 (0.7–1.4)

0.8 (0.5–1.1)

1.0 (0.7–1.4)

0.8 (0.6–1.1)**

Lactic dehydrogenase

U/l

274.5 (210.0–376.8)

215.5 (176.5–234.3)

277.5 (214.0–381.5)**

263.0 (206.0–342.5)

430.0 (323.0–579.0)**

272.0 (207.0–366.5)

292.0 (226.0–411.5)**

Alanine aminotransferase

U/l

27.0 (18.0–45.0)

26.0 (17.5–35.0)

27.5 (18.0–46.0)**

26.0 (18.0–43.0)

36.0 (23.3–62.0)**

28.0 (19.0–46.3)

25.0 (17.0–41.0)**

Hemoglobin

mmol/l

8.0 (7.1–8.7)

8.3 (7.6–8.9)

8.0 (7.1–8.7)**

8.0 (7.1–8.8)

7.6 (6.9–8.4)

8.1 (7.2–8.8)

7.7 (6.7–8.4)**

White blood cells

109/l

6.8 (5.1–9.4)

6.3 (4.7–7.3)

6.8 (5.1–9.5)**

6.8 (5.1–9.3)

7.9 (5.3–10.6)

6.7 (5.0–9.0)

7.4 (5.6–10.7)**

Neutrophil count

109/l

5.0 (3.5–7.4)

4.15 (3.3–5.2)

5.0 (3.5–7.5)**

4.9 (3.5–7.1)

6.1 (4.2–8.8)

4.8 (3.4–6.9)

5.7 (4.1–8.7)**

D dimer

mg/l

1.0 (0.6–2.4)

0.7 (0.7–1.9)

1.0 (0.6–2.4)**

0.9 (0.5–2.1)

1.4 (0.8–4.3)**

0.9 (0.5–2.1)

1.8 (0.8–4.4)**

Blood urea nitrogen

mmol/l

6.3 (4.3–9.9)

4.3 (3.8–6.7)

6.4 (4.4–10.0)**

6.3 (4.4–9.9)

6.8 (5.1–10.8)

5.7 (4.1–8.4)

9.8 (6.8–14.8)**

Creatinine

umol/l

81.5 (65.6–108.0)

67.0 (58.0–85.0)

83.0 (65.0–109.0)**

82.0 (65.0–107.0)

85.5 (67.0–111.3)

79.0 (63.0–100.0)

99.0 (75.6–149.0)**

Ferritin

ug/l

557.0 (203.0–1125.0)

167.0 (99.0–613.0)

570.0 (219.5–1145.0)**

399.0 (176.3–913.3)

1100.0 (741.0–1910.0)**

516.0 (204.0–1140.0)

649.0 (201.0–1110.0)**

Base excess

mmol/l

0.8 (− 1.4–3.0)

0.3 (− 0.9–2.7)

0.8 (− 1.4–3.1)**

0.7 (− 1.4–3.0)

1.0 (− 1.7–3.6)

0.8 (− 1.1–3.1)

0.6 (− 2.8–3.0)

HCO3

mEQ/l

25.2 (23.6–27.0)

25.0 (24.3–26.8)

25.2 (23.6–27.0)**

25.2 (23.6–26.9)

25.4 (23.6–27.4)**

25.3 (24.0–27.0)

24.9 (22.2–27.0)**

Lactate

mmol/l

1.1 (0.8–1.5)

1.2 (0.8–1.8)

1.1 (0.8–1.5)**

1.0 (0.8–1.5)

1.3 (1.0–1.7)**

1.0 (0.8–1.4)

1.3 (0.9–1.7)**

Arterial O2 saturation

%

0.94 (0.92–0.99)

0.95 (0.92–0.97)

0.94 (0.92–0.97)**

0.95 (0.92–0.97)

0.92 (0.91–0.94)**

0.95 (0.92–0.97)

0.93 (0.92–0.96)**

pCO2

mmHg

4.6 (4.1–5.1)

4.7 (4.4–5.0)

4.6 (4.1–5.1)**

4.6 (4.1–5.1)

4.7 (4.1–5.2)**

4.6 (4.1–5.1)

4.7 (4.0–5.2)**

pH

7.46 (7.43–7.49)

7.47 (7.43–7.49)

7.46 (7.43–7.49)**

7.46 (7.43–7.49)

7.47 (7.42–7.49)**

7.47 (7.43–7.49)

7.45 (7.41–7.49)**

pO2

mmHg

9.1 (8.0–10.9)

10.0 (7.9–10.7)

9.1 (8.0–10.9)**

9.4 (8.2–11.1)

8.3 (7.5–9.6)**

9.3 (8.2–11.1)

8.8 (7.8–10.2)**

Pulse

/min

83.0 (72.0–94.0)

86.0 (74.0–102.25)

83.0 (72.0–93.0)**

82.0 (71.0–92.0)

86.0 (76.0–97.0)

82.0 (72.0–93.0)

85.0 (72.8–98.3)**

Temperature

C

37.4 (36.8–38.1)

37.3 (36.6–38.0)

37.4 (36.8–38.1)**

37.3 (36.8–38.0)

37.6 (37.1–38.3)

37.4 (36.8–38.1)

37.3 (36.7–38.0)**

Early warning score

3.0 (2.0–6.0)

2.0 (1.0–4.0)

4.0 (2.0–6.0)**

3.0 (2.0–5.0)

6.0 (5.0–8.0)**

3.0 (2.0–5.0)

5.0 (3.0–6.0)**

Respiratory rate

/min

20.0 (17.0–22.0)

18.0 (16.0–20.0)

20.0 (18.0–22.0)**

20.0 (17.0–21.0)

24.0 (20.0–30.0)**

20.0 (17.0–22.0)

20.0 (18.0–24.0)**

Saturation

%

96.0 (94.0–98.0)

98.0 (96.5–99.0)

96.0 (94.0–97.0)**

96.0 (95.0–98.0)

94.0 (92.0–95.0)

96.0 (95.0–98.0)

95.0 (93.0–97.0)**

Is smoking

 %

4.8

0.5

13.1**

12.1

19.3

3.4

21.3**

  1. Furthermore, differential temporal features between survivors and non-survivors (in-hospital mortality) is presented. Continuous variables are presented as medians with (interquartile range).
  2. **p < 0.001 when subgroups are compared (e.g. hospitalized vs. non-hospitalized, ICU vs. non-ICU, survivors vs. non-survivors).