Table 1 Characteristics and source of genome-derived proteomes of kinetoplastids used in this work.

From: Total Ortholog Median Matrix as an alternative unsupervised approach for phylogenomics based on evolutionary distance between protein coding genes

Species name	Life cycle	Genome source	Protein sequence source¹	Publication	Genome size (Mb)	Number of sequences²
Angomonas deanei	Endosymbiont-bearing monoxenous	NCBI	Orf/blastx REFSEQ	PMID23560078	23	6255
Angomonas desouzai	Endosymbiont-bearing monoxenous	NCBI	Orf/blastx REFSEQ	PMID21420905	24.3	6282
Blechomonas ayalai	Monoxenous	TriTrypdb	TriTrypdb	PMID27021793	N/A	8037
Bodo saltans	Free living	NCBI	NCBI	PMID19068121	39.9	17,840
Crithidia acanthocephali	Monoxenous	NCBI	Orf/blastx REFSEQ	PMID23560078	33.8	11,800
Crithidia bombi	Monoxenous	NCBI	Orf/blastx REFSEQ	PMID29304093	31.4	7675
Crithidia expoeki	Monoxenous	NCBI	Orf/blastx REFSEQ	PMID29304093	34	10,254
Crithidia mellificae	Monoxenous	NCBI	Orf/blastx REFSEQ	PMID24743507	58.7	7660
Crithidia fasciculata	Monoxenous	TriTrypdb	TriTrypdb	N/A	41.3	9489
Endotrypanum monterogeii	Dixenous	TriTrypdb	TriTrypdb	N/A	32.5	8285
Herpetomonas muscarum	Monoxenous	NCBI	Orf/blastx REFSEQ	N/A	30.8	10,297
Leishmania amazonensis	Dixenous	Unicamp	Unicamp	PMID23857904	31.3	7316
Leishmania arabica	Dixenous	TriTrypdb	TriTrypdb	N/A	31.3	8646
Leishmania aethiopica	Dixenous	TriTrypdb	TriTrypdb	N/A	32.6	8722
Leishmania enriettii	Dixenous	TriTrypdb	TriTrypdb	N/A	30.8	8731
Leishmania gerbilli	Dixenous	TriTrypdb	TriTrypdb	N/A	31.4	8599
Leishmania braziliensis	Dixenous	NCBI	NCBI	PMID26384787	35.2	8151
Leishmania donovani	Dixenous	NCBI	NCBI	PMID22038251	32.4	7960
Leishmania infantum	Dixenous	NCBI	NCBI	PMID29273719	32.4	8141
Leishmania major	Dixenous	NCBI	NCBI	PMID16020728	32.3	8306
Leishmania mexicana	Dixenous	NCBI	NCBI	PMID26452044	32.1	8137
Leishmania panamensis	Dixenous	NCBI	NCBI	PMID25707621	31	7742
Leishmania peruviana	Dixenous	NCBI	Orf/blastx REFSEQ	PMID26384787	33.4	7155
Leptomonas pyrrhocoris	Monoxenous	NCBI	NCBI	PMID27021793	30.4	9284
Leptomonas seymouri	Monoxenous	NCBI	NCBI	PMID26317207	27.1	8485
Leishmania tarentolae	Dixenous	TriTrypdb	TriTrypdb	N/A	N/A	8305
Leishmania tropica	Dixenous	TriTrypdb	TriTrypdb	N/A	32.3	8824
Leishmania turanica	Dixenous	TriTrypdb	TriTrypdb	N/A	32.2	8608
Trypanosoma evansi	Monoxenous	TriTrypdb	TriTrypdb	N/A	N/A	12,838
Lotmaria passim	Monoxenous	NCBI	NCBI	PMID26146231	27.7	4850
Perkinsela sp.	Obligate endosymbiont	NCBI	NCBI	PMID28916813	9.5	5192
Phytomonas francai	Dixenous (plants)	NCBI	Orf/blastx REFSEQ	PMID28082482	17.7	6410
Phytomonas sp.	Dixenous (plants)	NCBI	NCBI	PMID24516393	18	4905
Phytomonas serpens	Dixenous (plants)	TriTrypdb	TriTrypdb	N/A	25.7	7329
Strigomonas galati	Endosymbiont-bearing monoxenous	NCBI	Orf/blastx REFSEQ	PMID24015778	27.2	6785
Strigomonas culicis	Endosymbiont-bearing monoxenous	NCBI	Orf/blastx REFSEQ	PMID23560078	25.4	6778
Strigomonas oncopelti	Endosymbiont-bearing monoxenous	NCBI	Orf/blastx REFSEQ	PMID24015778	25	9642
Trypanosoma brucei	Dixenous	NCBI	NCBI	PMID16020726	26.5	8132
Trypanosoma congolense	Dixenous	NCBI	NCBI	N/A	39.2	19,062
Trypanosoma cruzi	Dixenous	NCBI	NCBI	PMID24482508	30.4	7659
Trypanosoma equiperdum	Dixenous	NCBI	NCBI	PMID28138343	26.2	10,001
Trypanosoma grayi	Dixenous	NCBI	NCBI	PMID25977781	20.9	10,576
Trypanosoma rangeli	Dixenous	NCBI	NCBI	PMID25233456	18.1	7331
Trypanosoma theileri	Dixenous	TriTrypdb	TriTrypdb	N/A	29.8	11,312
Trypanosoma vivax	Dixenous	TriTrypdb	TriTrypdb	N/A	24.7	11,362
Paratrypanosoma	Monoxenous	NCBI	NCBI	PMID29078369	27.5	9606

1. Protein sequences were obtained from NCBI, TriTrypDB, or deduced from genome by obtaining open reading frames and adjusting starting Met by blastx to Protozoa-Refseq NCBI database; 2. After clusterization at 99% and removal of sequences smaller than 50 aa. N/A: not available.

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Table 1 Characteristics and source of genome-derived proteomes of kinetoplastids used in this work.

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