Table 2 Estimates of model parameters for the COVID-19 outbreak within mainland China.
From: Transmission dynamics and control measures of COVID-19 outbreak in China: a modelling study
Name | Definition | Prior | Posterior after distributing 1290 deaths to: | |
|---|---|---|---|---|
Before 20 February | Whole period | |||
τβ | Time point when the transmission rate is estimated to change because of control measures | U[60,143]* | 70.6 (69.2,71.9) | 71.4 (70.2,72.0) |
βa | Daily transmission rate before τβ | U[0.020,1.00] | 0.523 (0.311,0.691) | 0.512 (0.292,0.674) |
βb | Daily trasnmission rate after τβ | U[0.001,0.20] | 0.009 (0.001,0.031) | 0.007 (0.001,0.031) |
R0,1 | Reproduction number before τβ | – | 2.33 (1.96,3.69) | 2.20 (1.85,4.10) |
R0_con | R0 due to confirmed cases before τβ | – | 0.042 (0.017,0.111) | 0.037 (0.013,0.107) |
R0_und | R0 due to undetected cases before τβ | – | 2.27 (1.92,3.65) | 2.16 (182,4.07) |
R0,2 | Reproduction number after τβ | – | 0.036 (0.006,0.100) | 0.027 (0.006,0.094) |
I0 | Initial number of infectious people on 1/12/2019 | U[1,500] | 8.7 (2.7,49.1) | 14.3 (2.4,67.8) |
Initial total number of people infected with the virus on 1/12/2019 | – | 40.9 (12.8,207.2) | 71.1 (12.4,304.4) | |
τθ | Time point when the case ascertainment rate is estimated to change | U[40,62]* | 49.3 (47.1,51.6) | 50.1 (48.0,52.8) |
θ1,a | Case ascertainment rate before τθ | U[1%,25%] | 3.48% (1.74%,8.33%) | 3.47% (1.35%,8.96%) |
θ1,b | Case ascertainment rate after τθ | U[25%,100%] | 36.61% (26.07%,55.39%) | 38.29% (30.44%,55.67%) |
τF | Time point when the confirmed case-fatality rate (cCFR) is estimated to change | U[65,95]* | 77.0 (75.3,78.0) | 77.4 (76.0,78.9) |
θ2,a | Mortality rate among confirmed cases (cCFR1) before τF | U[0.5%,50%] | 9.61% (8.12%,11.36%) | 8.56% (7.51%,10.01%) |
θ2,b | Mortality rate among confirmed cases (cCFR2) after τF | U[0.1%,50%] | 0.67% (0.45%,0.97%) | 1.28% (0.96%,2.35%) |
D1 | Average infectious period before hospitalization (days) | U[2.0,10] | 2.28 (2.01,3.12) | 2.12 (2.0,2.71) |
D1+Du | Average infectious period of undetected infections (days) | U[3.0,25.0] | 4.44 (3.19,11.71) | 4.31 (3.11,13.43) |
ηHOS | Dispersion parameter for reported cases | U[1.01,1500] | 76.0 (50.2,122.8) | 82.8 (53.9,134.1) |
ηDeath | Dispersion parameter for deaths | U[1.01,5000] | 3.5 (2.4,5.2) | 4.0 (2.8,5.9) |
ηRecovery | Dispersion parameter for recoveries | U[1.01,1500] | 144.8 (102.8,205.6) | 150.3 (104.7,215.37) |
IFR1 | Infection fatality rate (θ1,aθ2,a) before τθ | – | 0.33% (0.17%,0.85%) | 0.30% (0.11%,0.81%) |
IFR2 | Infection fatality rate (θ1,bθ2,a) between τθ and τF | – | 3.51% (2.60%,5.12%) | 3.31% (2.47%,4.89%) |
IFR3 | Infection fatality rate (IRF2 = θ1,bθ2,b) after τF | – | 0.24% (0.15%,0.41%) | 0.50% (0.34%,0.86%) |