Table 2 Estimates of model parameters for the COVID-19 outbreak within mainland China.

From: Transmission dynamics and control measures of COVID-19 outbreak in China: a modelling study

Name

Definition

Prior

Posterior after distributing 1290 deaths to:

Before 20 February

Whole period

τβ

Time point when the transmission rate is estimated to change because of control measures

U[60,143]*

70.6 (69.2,71.9)

71.4 (70.2,72.0)

βa

Daily transmission rate before τβ

U[0.020,1.00]

0.523 (0.311,0.691)

0.512 (0.292,0.674)

βb

Daily trasnmission rate after τβ

U[0.001,0.20]

0.009 (0.001,0.031)

0.007 (0.001,0.031)

R0,1

Reproduction number before τβ

2.33 (1.96,3.69)

2.20 (1.85,4.10)

R0_con

R0 due to confirmed cases before τβ

0.042 (0.017,0.111)

0.037 (0.013,0.107)

R0_und

R0 due to undetected cases before τβ

2.27 (1.92,3.65)

2.16 (182,4.07)

R0,2

Reproduction number after τβ

0.036 (0.006,0.100)

0.027 (0.006,0.094)

I0

Initial number of infectious people on 1/12/2019

U[1,500]

8.7 (2.7,49.1)

14.3 (2.4,67.8)

 

Initial total number of people infected with the virus on 1/12/2019

40.9 (12.8,207.2)

71.1 (12.4,304.4)

τθ

Time point when the case ascertainment rate is estimated to change

U[40,62]*

49.3 (47.1,51.6)

50.1 (48.0,52.8)

θ1,a

Case ascertainment rate before τθ

U[1%,25%]

3.48% (1.74%,8.33%)

3.47% (1.35%,8.96%)

θ1,b

Case ascertainment rate after τθ

U[25%,100%]

36.61% (26.07%,55.39%)

38.29% (30.44%,55.67%)

τF

Time point when the confirmed case-fatality rate (cCFR) is estimated to change

U[65,95]*

77.0 (75.3,78.0)

77.4 (76.0,78.9)

θ2,a

Mortality rate among confirmed cases (cCFR1) before τF

U[0.5%,50%]

9.61% (8.12%,11.36%)

8.56% (7.51%,10.01%)

θ2,b

Mortality rate among confirmed cases (cCFR2) after τF

U[0.1%,50%]

0.67% (0.45%,0.97%)

1.28% (0.96%,2.35%)

D1

Average infectious period before hospitalization (days)

U[2.0,10]

2.28 (2.01,3.12)

2.12 (2.0,2.71)

D1+Du

Average infectious period of undetected infections (days)

U[3.0,25.0]

4.44 (3.19,11.71)

4.31 (3.11,13.43)

ηHOS

Dispersion parameter for reported cases

U[1.01,1500]

76.0 (50.2,122.8)

82.8 (53.9,134.1)

ηDeath

Dispersion parameter for deaths

U[1.01,5000]

3.5 (2.4,5.2)

4.0 (2.8,5.9)

ηRecovery

Dispersion parameter for recoveries

U[1.01,1500]

144.8 (102.8,205.6)

150.3 (104.7,215.37)

IFR1

Infection fatality rate (θ1,aθ2,a) before τθ

0.33% (0.17%,0.85%)

0.30% (0.11%,0.81%)

IFR2

Infection fatality rate (θ1,bθ2,a) between τθ and τF

3.51% (2.60%,5.12%)

3.31% (2.47%,4.89%)

IFR3

Infection fatality rate (IRF2 = θ1,bθ2,b) after τF

0.24% (0.15%,0.41%)

0.50% (0.34%,0.86%)

  1. The 1290 deaths within Hubei province added on 17th April 2020 were distributed over either the period before 17th April (i.e., the whole period) or before 20th February 2020 in proportional to the daily number of deaths reported before 17th April 2020. The relative infectiousness of undetected cases compared to confirmed cases ξ = 1 (i.e., both undetected and confirmed infections are of the same infectiousness).
  2. The estimated values of model parameters are nearly the same for both ways of distributing 1290 deaths added on 17th April 2020 by Chinese National Health Commission except for estimates of cCFR2 and IFR3.
  3. *The epidemic was assumed to start from 1st Dec 20191.