Table 1 Baseline characteristics of cancer survivors at enrollment according to body mass index (BMI) categories in the National Health Insurance-Health Screening cohort (NHIS-HEALS) database.
From: Risk of coronary heart disease among cancer survivors with different prediagnosis body mass index
Prediagnosis BMI (kg/m2) | ||||||
|---|---|---|---|---|---|---|
< 18.5 (n = 621) | 18.5–22.9 (n = 5305) | 23.0–24.9 (n = 3392) | ≥ 25.0 (n = 4182) | Total (n = 13,500) | p valueg | |
Age, mean (SD) | 67.5 (9.55) | 63.1 (9.94) | 61.9 (9.61) | 60.7 (9.35) | 62.3 (9.78) | < 0.001 |
Sex | ||||||
Male | 494 (79.6) | 3872 (73.0) | 2365 (69.7) | 2696 (64.5) | 9427 (69.8) | < 0.001 |
Female | 127 (20.4) | 1433 (27.0) | 1027 (30.3) | 1486 (35.5) | 4073 (30.2) | |
Residential area | ||||||
Capital | 73 (11.8) | 783 (14.8) | 569 (16.8) | 700 (16.7) | 2125 (15.7) | < 0.001 |
Metropolitan | 222 (35.8) | 2143 (40.4) | 1434 (42.3) | 1812 (43.3) | 5611 (41.6) | |
City/Town | 326 (52.4) | 2379 (44.8) | 1389 (40.9) | 1670 (40.0) | 5764 (42.7) | |
Insurance premiuma | ||||||
1Q | 115 (18.5) | 954 (17.9) | 514 (15.2) | 631 (15.1) | 2214 (16.4) | < 0.001 |
2Q | 176 (28.3) | 1173 (22.1) | 702 (20.7) | 858 (20.5) | 2909 (21.5) | |
3Q | 175 (28.2) | 1542 (29.1) | 978 (28.8) | 1267 (30.3) | 3962 (29.4) | |
4Q | 155 (25.0) | 1636 (30.9) | 1198 (35.3) | 1426 (34.1) | 4415 (32.7) | |
Cigarette smoking | ||||||
Non-smoker | 305 (49.1) | 3004 (56.6) | 2065 (60.9) | 2780 (66.5) | 8154 (60.4) | < 0.001 |
Past smoker | 58 (9.3) | 513 (9.7) | 417 (12.3) | 478 (11.4) | 1466 (10.9) | |
Current smoker | 258 (41.6) | 1788 (33.7) | 910 (26.8) | 924 (22.1) | 3880 (28.7) | |
Alcohol consumption | ||||||
1–2 times/week | 421 (67.8) | 3564 (67.2) | 2332 (68.8) | 2945 (70.4) | 9262 (68.6) | < 0.001 |
3–4 times/week | 116 (18.7) | 1197 (22.6) | 803 (23.7) | 998 (23.9) | 3114 (23.1) | |
≥ 5 times/week | 84 (7.5) | 544 (10.2) | 257 (7.5) | 239 (5.7) | 1124 (8.3) | |
Physical activity | ||||||
1–2 times/week | 526 (84.7) | 4339 (81.8) | 2661 (78.5) | 3238 (77.4) | 10,764 (79.7) | < 0.001 |
3–4 times/week | 47 (7.6) | 562 (10.6) | 435 (12.8) | 571 (13.7) | 1615 (12.0) | |
≥ 5 times/week | 48 (7.7) | 404 (7.6) | 296 (8.7) | 373 (8.9) | 1121 (8.3) | |
Fasting serum glucose, mg/dL, mean, mean (SD) | 103.0 (51.3) | 101.9 (38.3) | 103.3 (36.1) | 105.3 (37.4) | 103.3 (38.2) | < 0.001 |
Total cholesterol, mg/dL, mean, mean (SD) | 174.3 (37.8) | 186.8 (38.6) | 195.3 (39.2) | 199.1 (40.0) | 192.2 (39.7) | < 0.001 |
Blood pressure, mmHg mean, mean (SD) | ||||||
SBP | 123.1 (19.0) | 126.6 (17.8) | 129.7 (17.7) | 131.7 (17.3) | 128.8 (17.8) | < 0.001 |
DBP | 75.8 (11.6) | 77.9 (10.9) | 80.1 (11.2) | 81.5 (11.2) | 79.5 (11.3) | < 0.001 |
Charlson comorbidity index | ||||||
0 | 103 (16.6) | 1014 (19.1) | 649 (19.2) | 801(19.2) | 2567 (19.0) | 0.479 |
1 | 205 (33.1) | 1859 (35.1) | 1176 (34.7) | 1428 (34.2) | 4668 (34.6) | |
≥ 2 | 311 (50.4) | 2424 (45.8) | 1563 (46.1) | 1951 (46.6) | 6249 (46.3) | |
ESC SCOREb | ||||||
Very high (≥ 10%) | 27 (4.3) | 240 (4.5) | 202 (5.9) | 256 (6.1) | 1328 (9.8) | < 0.001 |
High (5% ≤ SCORE < 10%) | 418 (67.3) | 2599 (49.0) | 1481 (43.7) | 1639 (39.2) | 5310 (39.3) | |
Moderate (1% ≤ SCORE < 5%) | 144 (23.2) | 1917 (36.1) | 1369 (40.4) | 1880 (44.9) | 6137 (45.5) | |
Low (SCORE < 1%) | 32 (5.2) | 549 (10.4) | 340 (10.0) | 407 (9.8) | 725 (5.4) | |
Family history of CVDc | 6 (1.1) | 79 (1.6) | 58 (1.9) | 72 (1.9) | 215 (1.8) | < 0.001 |
Presence of depressiond | 40 (6.4) | 301 (5.7) | 198 (5.8) | 192 (4.6) | 731 (5.4) | < 0.001 |
Medication usee | ||||||
Aspirin | 147 (23.7) | 1409 (26.6) | 1166 (34.4) | 1718 (41.1) | 1052 (7.8) | < 0.001 |
Statin | 37 (6.0) | 432 (8.1) | 384 (11.3) | 612 (14.6) | 1465 (10.9) | < 0.001 |
Anti-hypertensive drugs | 17 (2.7) | 286 (5.4) | 278 (8.2) | 471 (11.7) | 4815 (35.7) | < 0.001 |
Anti-diabetic drugs | 51 (8.2) | 517 (9.8) | 424 (12.5) | 625 (15.0) | 1617 (12.0) | < 0.001 |
NSAIDs | 215 (34.6) | 1839 (34.7) | 1187 (35.0) | 1574 (37.6) | 4440 (32.9) | < 0.001 |
First site of cancer at enrollment | ||||||
Lung cancer | 152 (24.5) | 987 (18.6) | 483 (14.2) | 505 (12.1) | 2127 (15.8) | < 0.001 |
Stomach cancer | 184 (29.6) | 1334 (25.2) | 813 (24.0) | 1032 (24.7) | 3363 (24.9) | < 0.001 |
Colorectal cancer | 88 (14.2) | 890 (16.8) | 621 (18.3) | 813 (19.4) | 2412 (17.9) | < 0.001 |
Liver cancer | 69 (11.1) | 770 (14.5) | 498 (14.7) | 664 (15.9) | 2001 (14.8) | < 0.001 |
Othersf | 184 (29.6) | 1818 (34.3) | 1233 (36.4) | 1469 (35.1) | 4704 (34.8) | < 0.001 |
