Table 3 Clinical characteristics of probable migraine and migraine according to the presence of cutaneous allodynia.
From: Prevalence and characteristics of cutaneous allodynia in probable migraine
PM | Migraine | |||||
|---|---|---|---|---|---|---|
PM with CA, N = 42 | PM without CA, N = 247 | p-value† | Migraine with CA, N = 20 | Migraine without CA, N = 105 | p-value† | |
Headache frequency per month | 3.3 ± 4.3 | 1.8 ± 3.6 | 0.017 | 5.6 ± 8.4 | 2.1 ± 3.5 | 0.857 |
Headache intensity (Visual Analogue Scale) | 6.0 (4.0–7.0)* | 5.0 (3.0–6.0)* | 0.002 | 7.0 (6.0–7.0)* | 6.0 (5.0–7.0)* | 0.033 |
Attack duration (hours) | 2.2 ± 0.9 | 1.5 ± 1.1 | < 0.001 | 9.1 ± 7.8 | 7.6 ± 6.6 | |
Unilateral pain | 19 (45.2) | 145 (58.6) | 0.097 | 14 (70.0) | 73 (69.5) | 0.937 |
Aggravation by movement | 27 (64.3) | 86 (34.8) | < 0.001 | 11 (55.0) | 48 (45.7) | 0.501 |
Pulsating quality | 31 (73.8) | 197 (86.4) | 0.337 | 15 (75.0) | 87 (82.8) | 0.547 |
Nausea | 38 (90.5) | 230 (93.1) | 0.467 | 19 (95.0) | 93 (88.6) | 0.448 |
Vomiting | 19 (45.2) | 117 (47.4) | 0.828 | 12 (60.0) | 44 (41.9) | 0.168 |
Photophobia | 25 (59.5) | 67 (27.1) | 0.017 | 8 (40.0) | 37 (35.2) | 0.755 |
Phonophobia | 29 (69.0) | 112 (45.3) | 0.007 | 11 (55.0) | 55 (52.4) | 0.917 |
Osmophobia | 21 (50.0) | 95 (38.5) | 0.202 | 7 (35.0) | 41 (39.0) | 0.624 |
Depression (PHQ-9 score) ≥ 10 | 22 (52.4) | 40 (16.2) | < 0.001 | 7 (35.0) | 17 (16.2) | 0.047 |
PHQ-9 score | 11.1 ± 5.5 | 7.8 ± 3.5 | 0.150 | 8.6 ± 4.9 | 7.9 ± 3.7 | 0.520 |
Anxiety (GAD-7 score) ≥ 7 | 14 (33.3) | 13 (5.3) | < 0.001 | 9 (45.0) | 11 (10.5) | < 0.001 |
GAD-7 score | 4.7 ± 5.0 | 2.0 ± 2.6 | 0.312 | 6.6 ± 5.4 | 2.2 ± 2.8 | < 0.001 |
HIT-6 score | 56.3 ± 7.2 | 48.3 ± 8.0 | < 0.001 | 61.5 ± 9.2 | 51.4 ± 7.9 | < 0.001 |
MIDAS score | 1.0 (0.0–10.0)* | 0.0 (0.0–1.0)* | 0.029 | 5.0 (2.0–13.8)* | 0.0 (0.0–2.0)* | < 0.001 |
Body mass index | 23.1 ± 2.4 | 23.0 ± 2.6 | 0.625 | 22.7 ± 2.5 | 22.8 ± 2.5 | 0.116 |
