Table 4 Factors associated with cutaneous allodynia in individuals with probable migraine in univariable and multivariable analyses.

From: Prevalence and characteristics of cutaneous allodynia in probable migraine

 

Probable migraine

Migraine

Univariable OR, 95% CI

Multivariable OR, 95% CI

Univariable OR, 95% CI

Multivariable OR, 95% CI

Sex (Female)

1.4 (0.7–2.7)

1.4 (0.6–3.2)

1.3 (0.5–3.5)

1.0 (0.3–3.8)

Age (year)

20–29

REF

REF

REF

REF

30–39

1.1 (0.4–3.5)

1.5 (0.4–5.6)

1.4 (0.3–6.4)

1.1 (0.2–5.9)

40–49

0.6 (0.2–1.7)

0.8 (0.2–2.9)

1.4 (0.3–6.8)

0.5 (0.1–3.3)

50–59

0.9 (0.3–2.5)

1.2 (0.3–2.9)

0.5 (0.07–3.4)

0.2 (0.2–1.7)

60–69

0.6 (0.2–2.0)

0.4 (0.1–2.3)

1.3 (0.3–7.8)

0.2 (0.1–4.9)

 > 70

1.3 (0.4–3.8)

1.4 (0.3–8.2)

0.0 (0.0–0.0)*

0.0 (0.0–0.0)*

Educational level

High school

REF

REF

REF

REF

Middle school or less

1.6 (0.6–4.2)

1.6 (0.4–6.3)

0.0 (0.0–0.0)

0.0 (0.0–0.0)

College or more

1.3 (0.6–2.7)

0.9 (0.3–2.4)

0.9 (0.3–2.4)

0.4 (0.1–1.5)

Headache frequency per month

 < 1

REF

REF

REF

REF

1–14

1.3 (0.7–2.5)

0.6 (0.2–1.3)

2.5 (0.9–7.3)

1.0 (0.3–3.8)

 ≥ 15

1.6 (0.2–15.4)

1.1 (0.1–11.9)

9.8 (1.6–59.9)

2.6 (0.4–18.6)

Headache intensity

Mild

REF

REF

REF

REF

Moderate

2.7 (1.3–5.8)

2.4 (1.1–5.4)

2.5 (1.6–4.0)

0.9 (0.2–4.6)

Severe

5.7 (1.9–16.8)

4.0 (1.1–13.9)

8.5 (4.4–16.1)

2.6 (0.4–18.6)

Anxiety (GAD-7 score ≥ 7)

9.0 (3.8–21.1)

5.2 (1.7–16.3)

11.3 (2.5–52.4)

11.6 (2.0–67.3)

Depression (PHQ-9 score ≥ 10)

5.7 (2.8–11.4)

3.3 (1.5–7.6)

2.8 (1.0–8.0)

1.1 (0.2–5.3)

  1. OR: odds ratio, CI, confidence interval, GAD-7: Generalized Anxiety Disorder-7, PHQ-9: Patient Health Questionnaire-9. REF: Reference.
  2. *No participant with migraine aged > 70 had cutaneous allodynia.
  3. No participant with migraine had an educational level of middle school or less.