Table 6 Summary of results for the basic and final population models.

From: Population pharmacokinetic modeling and clinical application of vancomycin in Chinese patients hospitalized in intensive care units

Parameter

 

95%CI

Basic model

CL (L/h) (RSE%)

2.63 (25.72)

2.43,2.85

%CV of CL

53.27%

/

RSEE% of CL

38.23

/

V (L) (RSE%)

55.32 (27.31)

52.32,58.21

%CV of V

43.15%

/

RSEE% of V

21.36

/

MAE (%)

32.62

23.61, 40.31

Final model

CL (L/h) (RSE%)

3.16 (56.01)

2.83, 3.40

%CV of CL

41.72%

/

θ1 (RSEE%)

0.78 (33.46)

/

θ2 (RSEE%)

0.036 (36.15)

/

θ3 (RSEE%)

0.007 (32.32)

/

θ4 (RSEE%)

0.43 (36.51)

/

θ5 (RSEE%)

0.067 (22.15)

/

θ6 (RSEE%)

0.41 (35.65)

/

V (l−1) (RSE%)

60.71(55.19)

53.15, 67.46

%CV of V

35.14%

/

θ7 (RSEE%)

46.47 (36.21)

/

θ8 (RSEE%)

0.04 (32.43)

/

θ9 (RSEE%)

0.07 (38.17)

/

θ10 (RSEE%)

0.16 (32.63)

/

MAE (%)

8.71

5.73, 19.23

  1. %CV as coefficient of variation; RSEE% as relative standard prediction error; θ as regression parameter; RSE% as relative standard error.
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