Figure 1

Plasmodium berghei ANKA and Salmonella enterica serovar Typhi coinfection model. In the malaria infection model developed, three groups of animals received an intraperitoneal dose of 106 erythrocytes infected with P. berghei ANKA on D0, and challenged with S_Typhi on D1. Group 1 received 105 S_Typhi CFUs on D1 (Pb + S_Typhi 105). Group 2 received 104 S_Typhi CFUs on D1 (Pb + S_Typhi 104), and Group 3 received 103 S_Typhi CFUs (Pb + S_ Typhi 103). Three other groups were challenged with only S_Typhi on D1, Group 4 (S_Typhi 105), Group 5 (S_Typhi 104) and Group 6 (S_Typhi 103). The animals were euthanized for the quantification of CFUs of the liver, spleen and intestine in SS-Agar at 37 °C. This experiment was replicated once.