Figure 6 | Scientific Reports

Figure 6

From: Preclinical assessment of a modified Occlutech left atrial appendage closure device in a porcine model

Figure 6

Histopathological examination of device and surrounding tissue at follow up. 12 wk fu: (A) Macroscopic evaluation Device sealing the LAA ostium is depicted. Connective tissue covered by an endothelial layer completely fills the device surface. (B) Thrombus Thrombus completely organized by connective tissue (arrow). (C) Membrane The membrane is completely covered with connective tissue that is covered by an endothelial monolayer (arrow). (D) Anchoring In the areas of device ingrowth (black arrow) a cell-rich connective tissue developed with discrete diffuse inflammation consisting of PMN and lymphocytes (asterisk). B-D hematoxylin–eosin (HE) staining.

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