Figure 3
From: Cerebrospinal fluid proteome shows disrupted neuronal development in multiple sclerosis
Cohort 1. Schematic description of ER modelling. The data are considered as two-pseudofactors, each on two levels, and the impact of one factor is omitted during exploration of the other. ER modelling allows data on all controls and all MS patients to be combined in multivariate analyses to identify (a) a disease-associated proteome pattern as well as (b) the proteome signature that drives group affiliation.
