Figure 1

NF is triggered by release of blood into SA space. (a) Group data representing the changes body temperature (TCORE) between baseline (pre-injection) and 120 min following (post-injection) direct injection of blood or artificial cerebrospinal fluid (aCSF), into the subarachnoid (SA) space. The injection of blood, but not aCSF, elicited an increase in TCORE. (b) Group data representing the time course of the changes in TCORE following perforation of the anterior cerebral artery (ACA), or the sham perforation procedure. The extravascular release of blood into the SA space, produced by the perforation of the ACA, led to a significant increase in TCORE. *p < 0.05.