Figure 3 | Scientific Reports

Figure 3

From: Sarcoplasmic reticular Ca2+-ATPase inhibition paradoxically upregulates murine skeletal muscle Nav1.4 function

Figure 3

Effects of 0.1 µM CPA on currents and related I–V relationships. (a–c) Families of current traces obtained from applications of depolarizing voltage steps to a patch (a) before, (b) 1 min and (c) 4 min after solution change to K–H containing 0.1 µM CPA. (d) The resulting peak currents are plotted against test voltage excursions to give current voltage (I–V) relationships as in Fig. 2, here illustrating a ~ 20% alteration in maximum peak current following the solution change.

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