Figure 1
From: The G127V variant of the prion protein interferes with dimer formation in vitro but not in cellulo

Schematic illustration of the recombinant prion proteins used for testing the hetero- and homodimerization of mPrP. Top scheme represents the structure of the mouse prion protein tagged with an mCherry (mCh), mPrP-mCh, with indication of the location for the G126V mutation. Lower scheme depicts the untagged mPrP, indicating the mutations used, pBpa incorporation (at either position 127 or 131) and/or G126V.