Figure 5
The relationship between DSDR and CDRN and the functions of the special categories. (A–C) Scatter plots of the percentage of IDDs in each species of the three superkingdoms (A, archaea; B, bacteria; C, eukaryotes). Each point represents a species. The dashed diagonal line represents the line where Y and X are equal. The equation in each sub-figure was obtained by fitting a straight line based on the data of all species of archaea (A), bacteria (B) and fungi or metazoa (C). (D–G) Scatter plots of the DSDR and CDRN values of the four example eukaryote species. Each point represents a domain. According to the values of DSDR and CDRN, all of protein domains were divided into 4 classes: I, II, III, IV. The sum of the percentages of class I and class IV domains is equivalent to the X value of the corresponding species in sub-figure C; the sum of the percentages of class I and class II domains is equivalent to the Y value of the corresponding species in sub-figure C. (H–I) Venn diagrams of the IDDs of the two classes (II, IV) of fungi (H) and metazoa (I). There is an overlap between the two classes because some of IDDs belong to different classes (II, or IV) in different species. (J) Venn diagrams of the significantly over-represented BP terms for the two classes (II, IV) of IDDs of fungi and metazoan. (K) Over- or under-representation analysis of BPs for the two classes (II, IV) of IDDs of fungi and metazoa. The methods of over- or under- representation analysis and the criterion for strength grading are the same as that of Fig. 3A. The dashed lines separate the significantly over-represented BP terms for each class.
