Table 1 Baseline characteristics (N = 4236).
Total | pTxN1 | pT1-4N0 | p value | ||
|---|---|---|---|---|---|
(n = 4236) | (n = 52) | (n = 4184) | |||
Follow-up duration | Median (range) | 43.79 (1.02–293.06) | 82.52 (1.35–136.24) | 43.69 (1.02–293.06) | |
Age at operation | Mean ± STD | 55.53 ± 12.42 | 53.56 ± 13.85 | 55.56 ± 12.41 | 0.249 |
Gender | Male | 3001 | 34 (65.4) | 2967 (70.9) | 0.383 |
Female | 1235 | 18 (34.6) | 1217 (29.1) | ||
Body mass index (kg/cm2) | Mean ± STD | 24.54 ± 3.36 | 23.28 ± 3.32 | 24.55 ± 3.36 | 0.009 |
Diabetes | Yes | 594 | 6 (11.5) | 588 (14.1) | 0.602 |
Hypertension | Yes | 1592 | 16 (30.8) | 1576 (37.7) | 0.294 |
Chronic renal failure | Yes | 86 | 1 (1.9) | 85 (2.0) | > .999 |
ECOG | 0,1,2 | 3410 | 42 (80.8) | 3368 (80.5) | > .999 |
3,4 | 57 | 0 (0.0) | 57 (1.4) | ||
ASA | 1 | 1417 | 11 (21.2) | 1406 (33.6) | 0.376 |
2 | 1716 | 22 (42.3) | 1694 (40.5) | ||
3 | 175 | 2 (3.9) | 173 (4.1) | ||
4 | 5 | 0 (0.0) | 5 (0.1) | ||
Hb | Median (IQR) | 13.9 (12.7–15) | 12.8 (11.2–13.9) | 13.9 (12.7–15.05) | < .001 |
Platelet | Median (IQR) | 229 (193–271) | 279.5 (216–321) | 229 (192–270) | < .001 |
Creatinine | Median (IQR) | 0.99 (0.81–1.1) | 0.95 (0.86–1.14) | 0.99 (0.81–1.1) | 0.807 |
Albumin | Median (IQR) | 4.4 (4.1–4.6) | 4.1 (3.7–4.3) | 4.4 (4.1–4.6) | < .001 |
AST | Median (IQR) | 21 (18–28) | 20 (14–25) | 21 (18–28) | 0.041 |
ALT | Median (IQR) | 21 (15–32) | 16 (12–26) | 21 (15–32) | 0.004 |
MDRD GFR | Median (IQR) | 75.5 (63.9–87.8) | 71.95 (59.55–86.1) | 75.5 (63.9–87.8) | 0.245 |
Tumor location | Lt | 2101 | 24 (46.2) | 2077 (49.6) | 0.687 |
Rt | 2056 | 28 (53.9) | 2028 (48.5) | ||
Bilat | 27 | 0 (0.0) | 27 (0.7) | ||
Nephrectomy | Open surgery | 1930 | 38 (73.1) | 1892 (45.2) | < .001 |
Laparoscopic | 2254 | 14 (26.9) | 2240 (53.5) | ||
Operative extent | Partial | 1851 | 4 (7.7) | 1847 (44.1) | < .001 |
Radical | 1382 | 28 (53.9) | 1354 (32.4) | ||
pT | T1 | 3393 | 14 (26.9) | 3379 (80.8) | < .001 |
T2 | 334 | 11 (21.2) | 323 (7.7) | ||
T3 | 486 | 26 (50.0) | 460 (11.0) | ||
T4 + Tx | 23 | 1 (1.9) | 22 (0.5) | ||
Histology | Clear cell | 3575 | 32 (61.5) | 3543 (84.7) | < .001 |
Non-clear cell | 602 | 17 (32.7) | 585 (14.0) | ||
Mixed | 45 | 1 (1.9) | 44 (1.1) | ||
Nuclear grade | Grade 1–2 | 2195 | 13 (25) | 2182 (52.2) | 0.003 |
Grade 3–4 | 1832 | 28 (53.9) | 1804 (43.1) | ||
Sarcomatoid differentiation | Yes | 78 | 5 (9.6) | 73 (1.7) | 0.003 |
Necrosis | Yes | 311 | 16 (30.8) | 295 (7.1) | < .001 |
Lymphovascular invasion | Yes | 159 | 18 (34.6) | 141 (3.4) | < .001 |
Capsular invasion | Yes | 718 | 16 (30.8) | 702 (16.8) | 0.008 |
