Table 2 Clinical outcomes of participants at M&S follow-up study by treatment group (N = 553).
LPV/r (n = 274) | 3TC (n = 279) | P value | |
|---|---|---|---|
Anthropometry | |||
Weight (kg) | 19.3 (17.6;20.8) | 19.2 (17.4;20.6) | 0.31 |
Height (cm) | 113.5 (110.0;117.0) | 113.2 (109.0;117.0) | 0.55 |
Head circumference (cm) | 51.5 (50.6;52.0) | 51.5 (50.5;52.2) | 0.91 |
WAZ | − 0.50 (− 1.07;− 0.01)† | − 0.55 (− 1.20;− 0.03)† | 0.24 |
HAZ | − 0.52 (− 1.19;0.01)† | − 0.55 (− 1.31;0.06)† | 0.65 |
BMI z-score | − 0.27 (− 0.87;0.31)† | − 0.41 (− 0.96;0.32)† | 0.17 |
Underweight (WAZ < − 2) | 12 (4.4%)† | 18 (6.5%)† | 0.28 |
Stunting (HAZ < − 2) | 14 (5.1%)† | 23 (8.3%)† | 0.14 |
Clinical examination | |||
At least one abnormality observed | 94 (34.6%)† | 87 (31.2%) | 0.40 |
Type of event | |||
Neurological system | 3 | 1 | |
Cardiac system | 11 | 2 | |
Respiratory system | 16 | 19 | |
Dental system | 48 | 51 | |
Abdomen and genital urinary | 18 | 19 | |
Sensory system | 29 | 20 | |
Medical history | |||
Any medical consultation in clinic or outpatient clinic (without being admitted) during the last year | 178 (65.2%)‡ | 190 (68.1%) | 0.22 |
Type of event§ | |||
Neurological (convulsions) | 6 | 4 | |
Cardiac | 0 | 0 | |
Gastrointestinal | 27 | 30 | |
Respiratory | 80 | 89 | |
Skin | 25 | 16 | |
Malaria | 76 | 82 | |
Malnutrition | 0 | 0 | |
Other | 31 | 44 | |
Unknown | 10 | 4 | |
Ever been admitted to hospital since the last trial visit | 58 (21.3%)† | 60 (21.5%) | 0.95 |
Type of event§ | |||
Neurological (convulsions) | 6 | 22 | |
Cardiac | 0 | 0 | |
Gastric | 18 | 22 | |
Respiratory | 19 | 20 | |
Skin | 0 | 0 | |
Malaria | 46 | 71 | |
Cerebral malaria | 14 | 7 | |
Malnutrition | 4 | 5 | |
Other | 18 | 13 | |
Unknown | 2 | 4 | |
