Figure 2 | Scientific Reports

Figure 2

From: Pluripotency and immunomodulatory signatures of canine induced pluripotent stem cell-derived mesenchymal stromal cells are similar to harvested mesenchymal stromal cells

Figure 2

ciMSCs and cAT-MSCs constitutively express immunomodulatory and anti-inflammatory factors. ciMSCs and cAT-MSCs have similar constitutive expression profiles, although ciMSCs express higher levels of iNOS and HGF, and lower levels of VEGF, than the cAT-MSCs. Inducible nitric oxide (iNOS); Indoleamine 2,3 dioxygenase (IDO); Galectin-9 (GAL-9); Cyclooxygenase-2 (COX-2); Transforming growth factor-β1 (TGF-β1); Prostaglandin receptor-2α (PTGER-2α); Hepatocyte growth factor (HGF); Vascular endothelial growth factor (VEGF) ; Interleukin-8 (IL-8) and Interleukin-1β (IL-1β). Significance is defined as: ns = not significant p > 0.05; *p ≤ 0.05; **p ≤ 0.005; ***p ≤ 0.0002; ****p ≤ 0.0001.

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