Table 3 Univariable and multivariable Cox Regression Analysis of the associations between HDL-Sz and HDL-C/P ratio with cardiovascular death.

From: Particle size and cholesterol content of circulating HDL correlate with cardiovascular death in chronic heart failure

 

HDL-Sz

HDL-C/P ratio

HR (95% CI)

P value

HR (95% CI)

P value

Unadjusted

1.36 (1.16–1.58)

 < 0.001

1.06 (1.03–1.09)

 < 0.001

Multivariable adjustment

Model 1

1.21 (1.01–1.47)*

0.041

1.04 (1.01–1.07)*

0.008

Model 2

1.22 (1.01–1.47)*

0.041

1.04 (1.01–1.07)*

0.008

  1. Hazard ratios for HDL-Sz reflect 1 SD change in a given measure.
  2. Model 1 Adjusted for age, sex, BMI, diabetes, arterial hypertension, vasculopathy, ischemic etiology, NYHA functional class III-IV, eGFR, Hemoglobin, NT-ProBNP, LDL-P and treatment with ACEi/ARB, Betablockers, statins and ICD.
  3. Model 2 Adjusted for Model 1 plus glycoprotein (Gly)-A, Gly-B and Gly-F.
  4. *Other independent predictors of the outcomes in these models besides HDL-Sz or HDL-C/P were age, ischaemic etiology and NT-proBNP.
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