Table 1 Membrane dipole potential changes (Δψd, mV) induced by the compounds studied on LUV made of lipid mixtures with the compositions indicated, at 23 °C. The values were calculated using Eq. (2) and the error was obtained considering the experimental error in Rex measurements and the uncertainty of the proportionality constant in Eq. (2). GlcResveratrol - 4-Glucosylresveratrol; 8G – 8-Glucosylgenistein.
From: C-Glucosylation as a tool for the prevention of PAINS-induced membrane dipole potential alterations
Δψd (mV) | POPC | POPC:cholesterol | POPC:cholesterol:PSM |
|---|---|---|---|
Phloretin | − 103 ± 34 | − 327 ± 100 | − 218 ± 69 |
Nothofagin | − 22 ± 12 | − 25 ± 24 | − 24 ± 16 |
Phlorizin | − 72 ± 22 | − 173 ± 53 | − 126 ± 45 |
Genistein | − 61 ± 19 | − 127 ± 66 | − 62 ± 23 |
8G | 4 ± 6 | − 7 ± 14 | − 5 ± 9 |
Resveratrol | − 32 ± 12 | − 76 ± 39 | − 80 ± 31 |
GlcResveratrol | 5 ± 5 | − 8 ± 14 | − 4 ± 9 |
