Figure 3
From: Plasma microRNA signature associated with retinopathy in patients with type 2 diabetes
Circulating miR-25-3p, miR-320b and miR-495-3p are associated with DR. (a) Univariate linear regression models showing log-linear trends of association between miRNAs and severity of DR. Grade I, no retinopathy (n = 10); Grade II, mild no-proliferative DR (NPDR, n = 5); Grade III, moderate NPDR (n = 5); Grade IV, severe NPDR (n = 7); Grade V, proliferative DR (n = 3). (b) Forest plot showing odds ratios and the 95% CI for association of the single miRNAs with presence of DR in univariate logistic models (upper) or after correction for age, sex, and HbA1c (lower). (c), Receiver-operating characteristic (ROC) curve derived from the logistic regression model developed on circulating miR-25-3p, miR-320b, and miR-495-3p. AUC, area under the curve.
