Figure 5 | Scientific Reports

Figure 5

From: Genomic mutations and changes in protein secondary structure and solvent accessibility of SARS-CoV-2 (COVID-19 virus)

Figure 5

Alignment of sequences having deletion mutations at positions M85-, V86- or K141-, S142-, F143-, which are major deletions in the ORF1ab protein (Table 2). The GenBank accession numbers are presented on the left while isolate names and collected dates are on the right. The numbers on top show the positions of AAs in the protein and isolates are ordered by collected dates. The first isolate having these deletions is USA-CA6/2020 (record MT044258 in second row), collected on 2020-01-27 in USA: CA. This is also the isolate having the largest number of deletions: five sequentially at G82-, H83-, V84-, M85-, V86- and three at K141-, S142-, F143-. The other patients followed were possibly infected by this first case but more data such as travel history are needed to confirm this hypothesis.

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