Table 1 Summary of SARS-CoV-2 mutations on each protein and secondary structure and relative solvent accessibility changes.
Proteins | AA length | Available | No mutation | No mutation rate | Delete | Insert | Nonsyn | Syn | Nonsyn/Syn | Structure change | Accessibility change |
|---|---|---|---|---|---|---|---|---|---|---|---|
ORF1ab | 7096 | 3726 | 68 | 0.02 | 170 | 6 | 8330 | 6540 | 1.27 | NA | NA |
S | 1273 | 4434 | 872 | 0.20 | 34 | 0 | 3711 | 670 | 5.54 | 164 | 184 |
ORF3a | 275 | 5527 | 2182 | 0.39 | 6 | 1 | 3400 | 277 | 12.27 | NA | NA |
E | 75 | 5852 | 5747 | 0.98 | 0 | 0 | 28 | 77 | 0.36 | 18 | 7 |
M | 222 | 5677 | 5128 | 0.90 | 0 | 0 | 121 | 444 | 0.27 | 30 | 8 |
ORF6 | 61 | 5792 | 5657 | 0.98 | 18 | 2 | 72 | 64 | 1.12 | NA | NA |
ORF7a | 121 | 5321 | 5164 | 0.97 | 15 | 0 | 106 | 56 | 1.89 | NA | NA |
ORF7b | 43 | 5175 | 5120 | 0.99 | 0 | 0 | 24 | 36 | 0.67 | NA | NA |
ORF8 | 121 | 5732 | 4292 | 0.75 | 0 | 8 | 1563 | 74 | 21.12 | NA | NA |
N | 419 | 5281 | 4051 | 0.77 | 15 | 0 | 1927 | 392 | 4.92 | 1678 | 37 |
ORF10 | 38 | 5891 | 5829 | 0.99 | 0 | 0 | 19 | 43 | 0.44 | NA | NA |
