Figure 4 | Scientific Reports

Figure 4

From: Comparison of intravenous sedation using midazolam during dental treatment in elderly patients with/without dementia: a prospective, controlled clinical trial

Figure 4

Changes in the end-tidal CO2 (etCO2) and bispectral index (BIS) values. (a) indicates the etCO2 values: 33 (30–36) mmHg just before sedation and 34 (33.5–39.5) mmHg just before the start of treatment after midazolam administration in the dementia-negative group; 35.5 (35–36.8) mmHg just before sedation and 37.5 (36–40.8) mmHg just before the start of treatment after midazolam administration in the dementia-positive group (P = 0.017). (b) indicates the BIS values: 90 (82.8–97) just before sedation and 72.5 (68.8–77.8) just before the start of treatment after midazolam administration (P = 0.005) in the dementia-negative group; 91 (87–98) just before sedation and 52 (37–85) just before the start of treatment after midazolam administration (P = 0.018) in the dementia-positive group.

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