Figure 5
Changes in the normalized tissue hemoglobin index (nTHI). (a) indicates the right nTHI values: 1.05 (0.99–1.11) just before sedation (baseline value), 1.02 (0.99–1.06) when OAA/S score of 2 was achieved after midazolam administration, and 1.02 (0.96–1.09) just before the start of treatment in the dementia-negative group; 1.02 (0.98–1.08) just before sedation (baseline value), 0.95 (0.85–0.97) when OAA/S score of 2 was achieved after midazolam administration, and 0.91 (0.83–0.99) just before the start of treatment in the dementia-positive group. (b) indicates the left nTHI values: 1.02 (0.99–1.10) just before sedation (baseline value), 1.03 (1.00–1.08) when OAA/S score of 2 was achieved after midazolam administration, and 1.01 (1.00–1.06) just before the start of treatment in the dementia-negative group; 1.05 (0.98–1.17) just before sedation (baseline value), 0.94 (0.87–1.02) when OAA/S score of 2 was achieved after midazolam administration, and 0.92 (0.79–1.01) just before the start of treatment in the dementia-positive group. The right nTHI values are significantly different among the three measurement points in the dementia group (P = 0.008, χ2 = 9.600), and post hoc analysis was performed (indicated in the figure). The left nTHI values showed no significant difference among the three measurement points in the dementia group (P = 0.097, χ2 = 4.667), but the left nTHI values suggest a decreasing trend after midazolam administration. Each comparison of data (measurement point 2 or 3) between those with and without dementia is close to significant.
