Figure 1 | Scientific Reports

Figure 1

From: Transient prenatal ruxolitinib treatment suppresses astrogenesis during development and improves learning and memory in adult mice

Figure 1

Behavioural, gross anatomical and histopathological assessments of pregnant mice underwent transient ruxolitinib treatment. (A) Analysis of weight (n = 3–7 per group for 1.5 day post-coitum and n = 3–6 per group for 20.5 day post-coitum; One-way ANOVA with Sidak's multiple comparisons), and normalised feed and water consumptions (n = 3–6 per group; One-way ANOVA with Dunnett's multiple comparisons) between G1 (0 mg/kg) vehicle control group and treated groups. (B) Representative figure for gross anatomical assessment and the weight of the kidney, liver and spleen (n = 3 per group; One-way ANOVA with Dunnett's multiple comparisons) harvested from G1-G6 pregnant mice. (C) Representative haematoxylin and eosin staining of kidney, liver, and spleen sections (n = 3 per group) from G1-G6 pregnant mice. All values represent mean ± SEM; *** denotes adjusted p < 0.001.

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