Figure 4
(A) Cyclic voltammograms of differentially modified electrodes in 1.0 mM Fe(CN)63−/4− and 0.1 M KCl solution at a scan rate of 100 mV/s. (a) Bare SPCE; (b) Au NPs/SPCE; (c) Au NCs/SPCE; (d) Au NP/MWCNTs-NH2/SPCE; (e) Au NC/MWCNTs-NH2/SPCE (f) probe-RNA/Au NC/MWCNTs-NH2 /SPCE; (g) hybridized-RNA/MWCNTs-NH2/SPCE. (B) Nyquist diagram of EIS corresponding to each step of the modification of the biosensor. (a) Bare SPCE; (b) Au NPs/SPCE; (c) Au NCs/SPCE; (d) Au NC/MWCNTs-NH2/SPCE; (e) probe-RNA/Au NC/MWCNTs-NH2/SPCE; (f) hybridized-RNA/MWCNTs-NH2 /SPCE. The inset displays the Randles circuit to fit the experimental EIS data.
