Figure 1 | Scientific Reports

Figure 1

From: A nationwide cohort study for comparative vascular safety of long-acting insulin analogue versus intermediate-acting human insulin in type 2 diabetes

Figure 1

Flowchart of the study population selection and identification. (1) “N” represents the number of patients, and “n” represents the number of stable use sets. (2) Matching steps: (1) Step 1: matched by the cohort entry time (i.e., matching of the index date between the two study drug groups; the index date refers to the first date of IAHI or LAIA use). (2) Step 2: matched by the utilization pattern of glucose-lowering agents within 1 year prior to the index date. (3) Step 3: matched by the propensity score estimated based on patient characteristics measured within 1 year prior to the index date.

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